Merocare SE

Merocare SE

MEROCARE SE is a novel antibiotic adjuvant entity (AAE) to combat antimicrobial resistance caused by multidrug resistance ESBL/MBL producing strains comprising of a Meropenam carbapenam class antibiotic, Sulbactam Sodium an irreversible β-lactamase inhibitor along with non antibiotic adjuvant Disodium Edetate for intravenous administration. Sulbactam sodium is a derivative of basic penicillin nucleus. The product does not contain any preservative and is for single use only. It is administered as intravenous injection. Each single dose 1.5 g vial of MEROCARE SE contains Meropenam 1000 mg, Sulbactam Sodium Ph. Eur. equivalent to Sulbactam 500 mg, Disodium Edetate Ph. Eur. 37.5 mg. MEROCARE SE, a novel antibiotic adjuvant entity comprising Meropenam, Sulbactam & Disodium edetate powder for solution for injection/Infusion is a synergistic antimicrobial antibiotic. Presence of Disodium Edetate synergizes the activity of meropenam and sulbactam as it helps in opening porin channels and allows more drug to enter periplasmic space resulting in enhanced killing.